Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 14/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675432 | 0.94 | POLB (0.39) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559838 | 0.90 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23666192 | 0.89 | ELANE (0.40) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL24440871 | 0.89 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL20275159 | 0.88 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559829 | 0.87 | POLB (0.47) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL20923612 | 0.86 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25936691 | 0.86 | HTT (0.41) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19683314 | 0.85 | ELANE (0.38) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23350596 | 0.85 | POLB (0.36) | POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3839008-A1 | LIQUID CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3604481-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2020-02-05 | — | — | EP | disclosed |