Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21694733 | 1.00 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL7619926 | 0.84 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL4060717 | 0.84 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL4060709 | 0.84 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL7619930 | 0.84 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| SCHEMBL4060712 | 0.84 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BHRH3KDM1A | |
| Hydrochloric Acid SCHEMBL16535577 | 0.82 | SIGMAR1 (0.58) | HTR2CKDM1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL16536407 | 0.82 | SIGMAR1 (0.58) | HTR2CKDM1ASIGMAR1 | |
| SCHEMBL10357561 | 0.78 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL28599008 | 0.75 | HTR2A (0.45) | HTR2AHTR2CHTR2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025646-A1 | AN OMEGA-TRANSAMINASE ENZYME | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2020-02-06 | — | — | WO | disclosed |