Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060717 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| SCHEMBL4060709 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| SCHEMBL7619930 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| SCHEMBL7619926 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL16536407 | 0.98 | SIGMAR1 (0.58) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL16535577 | 0.98 | SIGMAR1 (0.58) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 | |
| SCHEMBL21694733 | 0.84 | HTR2A (0.49) | SIGMAR1KDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL21694751 | 0.84 | HTR2A (0.49) | SIGMAR1KDM1AHTR2CHTR2AHTR2B | |
| SCHEMBL1388099 | 0.84 | SIGMAR1 (0.55) | SIGMAR1HTR2CHTR2AHTR2BHRH3 | |
| SCHEMBL5815432 | 0.81 | SLC6A2 (0.62) | SIGMAR1MAOBKDM1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002500211-A | — | — | 2002-01-08 | — | — | JP | claimed |
| US-6268535-B1 | REACTING BENZENE SUBSTITUTED UNSATURATED CARBOXYLIC ACID IN PRESENCE OF FRIEDEL-CRAFT CATALYST WITH BENZENE COMPOUND TO FORM 3-ARYL-3-PHENYL-1-PROPANOIC ACID REACTING TO FORM 3-ARYL INDAN; REDUCING, REACTING WITH AMINE TO FORM 3-ARYLINDANAMINE | PHARM-ECO LABORATORIES, INC. | 2001-07-31 | — | — | US | claimed |
| EP-1044184-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | Pharm-Eco Laboratoires, Incorporated (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999035119-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | PHARM-ECO LABORATORIES, INC. (US) | 1999-07-15 | — | — | WO | claimed |
| EP-0076669-A1 | Novel 3-phenyl-1-indanamines, pharmaceutical compositions and methods of preparation | KEFALAS A/S (DK) | 1983-04-13 | — | — | EP | claimed |
| EP-3830253-A1 | AN OMEGA-TRANSAMINASE ENZYME | University College Cork-National University of Ireland Cork (IE) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020025646-A1 | AN OMEGA-TRANSAMINASE ENZYME | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2020-02-06 | — | — | WO | disclosed |
| EP-3604507-A1 | AN OMEGA-TRANSAMINASE ENZYME | University College Cork-National University of Ireland, Cork (IE) | 2020-02-05 | — | — | EP | disclosed |
| EP-2061748-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS | Office Of Intellectual Property And Technology (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1326865-B1 | AZA- AND POLYAZA-NAPHTHALENYL CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO INC (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008027740-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS | OFFICE OF INTELLECTUAL PROPERTY AND TECHNOLOGY (US) | 2008-03-06 | — | — | WO | disclosed |
| EP-1347967-B1 | NOVEL BENZAZEPINES AND RELATED HETEROCYCLIC DERIVATIVES WHICH ARE USEFUL AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-12-19 | — | — | EP | disclosed |
| WO-1996039399-A1 | STEREOSELECTIVE METHOD FOR SYNTHESIZING DOLAPHENINE | PHARM-ECO LABORATORIES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| EP-0144235-A2 | N6-(1- and 2-benzocycloalkyl) adenosines, pharmaceutical compositions comprising the same and a process for the production thereof | WARNER-LAMBERT COMPANY (US) | 1985-06-12 | — | — | EP | disclosed |
| EP-0035363-B1 | INDANE DERIVATIVES, METHODS OF THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | KEFALAS A/S (DK) | 1985-05-02 | — | — | EP | disclosed |
| US-4443448-A | ANALGESICS, ANTIDEPRESSANTS, NEUROLEPTICS | KEFALAS A/S (DK) | 1984-04-17 | — | — | US | disclosed |
| EP-0076669-A1 | Novel 3-phenyl-1-indanamines, pharmaceutical compositions and methods of preparation | KEFALAS A/S (DK) | 1983-04-13 | — | — | EP | disclosed |
| EP-0076669-A1 | Novel 3-phenyl-1-indanamines, pharmaceutical compositions and methods of preparation | KEFALAS A/S (DK) | 1983-04-13 | — | — | EP | disclosed |
| EP-0076669-A1 | Novel 3-phenyl-1-indanamines, pharmaceutical compositions and methods of preparation | KEFALAS A/S (DK) | 1983-04-13 | — | — | EP | disclosed |
| EP-0035363-A1 | Indane derivatives, methods of their preparation and compositions containing them | KEFALAS A/S (DK) | 1981-09-09 | — | — | EP | disclosed |