Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454729 | 0.85 | HTT (0.41) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18138134 | 0.81 | KMT2A (0.36) | KMT2AMEN1CYP1A2MAPTCYP2C9 | |
| SCHEMBL25018193 | 0.81 | HTT (0.40) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1870550 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL16983769 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL379163 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL6046844 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL37833 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL4960230 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 | |
| SCHEMBL905404 | 0.77 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTPSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200041437-A1 | BIOSENSORS WITH pH-INDEPENDENT REDOX MOIETIES | ECCRINE SYSTEMS, INC. (US) | 2020-02-06 | — | — | US | disclosed |