Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454729 | 0.96 | HTT (0.41) | HTTALDH1A1ABL1RIN1PSMB8 | |
| SCHEMBL21695021 | 0.81 | KMT2A (0.38) | HTTALDH1A1ABL1RIN1PSMB8 | |
| SCHEMBL10309800 | 0.79 | NAAA (0.46) | SMN1; SMN2LMNAKDM4E | |
| SCHEMBL18138134 | 0.79 | KMT2A (0.36) | HTTALDH1A1ABL1RIN1PSMB8 | |
| Hydrochloric Acid SCHEMBL29517283 | 0.78 | KDM4A (0.49) | HTTALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18356778 | 0.77 | NAAA (0.53) | KMT2ASMN1; SMN2 | |
| SCHEMBL15176976 | 0.77 | L3MBTL1 (0.48) | HTTALDH1A1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL34383 | 0.77 | SMN1; SMN2 (0.36) | HTTPSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL22777675 | 0.77 | SMN1; SMN2 (0.36) | HTTPSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL290461 | 0.77 | SMN1; SMN2 (0.40) | HTTALDH1A1PSMB8PSMB5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578265-B2 | AIEgens for cancer cell imaging | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578265-B2 | AIEgens for cancer cell imaging | CD4, MKI67, CCNB1 | HTT 3082/4885ALDH1A1 982/4885ABL1 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.