Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18135633 | 0.92 | KMT2A (0.33) | KMT2ASMN1; SMN2KDM4AKDM2ACHAT | |
| SCHEMBL14454729 | 0.83 | HTT (0.41) | KMT2ASMN1; SMN2HTTMEN1APAF1 | |
| SCHEMBL21695021 | 0.81 | KMT2A (0.38) | KMT2ASMN1; SMN2HTTMEN1APAF1 | |
| Hydrochloric Acid SCHEMBL29517283 | 0.80 | KDM4A (0.49) | KMT2ASMN1; SMN2KDM4AKDM2AHTT | |
| SCHEMBL25018193 | 0.79 | HTT (0.40) | KMT2ASMN1; SMN2HTTMEN1ALDH1A1 | |
| SCHEMBL379163 | 0.75 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1PSMB8 | |
| SCHEMBL1870550 | 0.75 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1PSMB8 | |
| SCHEMBL6046844 | 0.75 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1PSMB8 | |
| SCHEMBL16983769 | 0.75 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1PSMB8 | |
| SCHEMBL37833 | 0.75 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160299078-A1 | Specific Detection and Quantification of Cardiolipin and Isolated Mitochondria by Positively Charged AIE Fluorogens and Method of Manufacturing Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-10-13 | — | — | US | disclosed |