Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21695270 | 0.88 | MAP3K12 (0.67) | MAP3K12 | |
| SCHEMBL20340897 | 0.87 | MAP3K12 (0.74) | MAP3K12 | |
| SCHEMBL16210488 | 0.85 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL21695278 | 0.84 | MAP3K12 (0.66) | MAP3K12 | |
| SCHEMBL21695280 | 0.83 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL20115399 | 0.83 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL20147765 | 0.82 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL21695313 | 0.82 | MAP3K12 (0.60) | MAP3K12 | |
| SCHEMBL21695315 | 0.82 | MAP3K12 (0.62) | MAP3K12 | |
| SCHEMBL21695290 | 0.81 | MAP3K12 (0.61) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47848-E1 | Biheteroaryl compounds and uses thereof | GENENTECH, INC. (US) | 2020-02-11 | — | — | US | disclosed |