Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600848 | 0.83 | PI4KB (0.42) | GRM5SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL21695368 | 0.82 | GRM5 (0.45) | GRM5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL22793354 | 0.82 | GRM5 (0.38) | GRM5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL20718417 | 0.82 | GRM5 (0.38) | GRM5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL2642653 | 0.81 | GRM5 (0.44) | GRM5LMNAKMT2ANPC1RAB9A | |
| SCHEMBL9830946 | 0.78 | KMT2A (0.41) | GRM5KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL18236169 | 0.78 | GRM5 (0.42) | GRM5NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22550476 | 0.77 | KMT2A (0.40) | GRM5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL22550401 | 0.77 | KMT2A (0.40) | GRM5KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL22550537 | 0.77 | KMT2A (0.40) | GRM5KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556889-B1 | Salvinorin derivatives | Blue Sky Pharmaceuticals, LLC (US) | 2020-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556889-B1 | Salvinorin derivatives | OPRD1, OPRK1, OPRL1 | GRM5 473/4885LMNA 3012/4885KMT2A 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.