Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828897 | 0.80 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL829205 | 0.76 | P2RX7 (0.32) | — | |
| SCHEMBL8285564 | 0.72 | CYP11B1 (0.38) | OPRL1 | |
| SCHEMBL1670992 | 0.71 | — | — | |
| SCHEMBL829419 | 0.71 | — | — | |
| SCHEMBL3315162 | 0.70 | CXCR4 (0.40) | OPRL1 | |
| SCHEMBL469266 | 0.69 | CYP19A1 (0.31) | OPRL1 | |
| SCHEMBL20825128 | 0.68 | — | — | |
| SCHEMBL30584967 | 0.68 | CXCR4 (0.46) | — | |
| SCHEMBL14037800 | 0.68 | CXCR4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |