Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469266 | 0.81 | CYP19A1 (0.31) | OPRL1 | |
| SCHEMBL829205 | 0.81 | P2RX7 (0.32) | — | |
| SCHEMBL21696801 | 0.80 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL1670992 | 0.76 | — | — | |
| SCHEMBL829419 | 0.76 | — | — | |
| SCHEMBL8285564 | 0.70 | CYP11B1 (0.38) | OPRL1 | |
| SCHEMBL6177530 | 0.69 | HTR2A (0.36) | — | |
| SCHEMBL20825128 | 0.69 | — | — | |
| SCHEMBL10297756 | 0.68 | OPRL1 (0.37) | OPRL1 | |
| SCHEMBL11421179 | 0.68 | OPRL1 (0.37) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143403-B2 | CGRP receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20120010402-A1 | CGRP Receptor Antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010402-A1 | CGRP Receptor Antagonists | CALCRL, BDKRB2, CALCR | OPRL1 14/4885CBR1 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.