Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563115 | 0.82 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL2861477 | 0.76 | LMNA (0.44) | PIK3CD | |
| SCHEMBL21696895 | 0.75 | ACE (0.40) | PIK3CD | |
| SCHEMBL947534 | 0.74 | CHRM2 (0.42) | PIK3CD | |
| SCHEMBL28923086 | 0.71 | — | — | |
| SCHEMBL28923085 | 0.71 | — | — | |
| SCHEMBL1106465 | 0.70 | GAA (0.34) | — | |
| SCHEMBL8272700 | 0.67 | — | — | |
| SCHEMBL24568169 | 0.67 | POLB (0.33) | — | |
| SCHEMBL20739439 | 0.64 | SMN1; SMN2 (0.34) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |