Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110370 | 0.90 | ALDH1A1 (0.39) | ACEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12563115 | 0.80 | PIK3CD (0.34) | GAACYP11B2MAPTPIK3CD | |
| SCHEMBL10959845 | 0.77 | LMNA (0.51) | ACEKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL951298 | 0.77 | LMNA (0.51) | ACEKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL908022 | 0.76 | PIK3CD (0.46) | ACEKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3728882 | 0.75 | LMNA (0.46) | ACEKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL21696899 | 0.75 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL29902862 | 0.75 | CYP11B2 (0.39) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11187859 | 0.74 | LMNA (0.45) | ACEKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28109752 | 0.74 | LMNA (0.45) | ACEKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |