Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820758 | 0.89 | CYP3A4 (0.64) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL10144672 | 0.89 | CYP3A4 (0.64) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL7302729 | 0.89 | CYP3A4 (0.64) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL17048548 | 0.86 | P2RX7 (0.50) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL21696782 | 0.85 | FKBP1A (0.61) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL18885617 | 0.83 | P2RX7 (0.49) | ALDH1A1SMN1; SMN2F2AADAT | |
| SCHEMBL18882736 | 0.83 | P2RX7 (0.47) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM | |
| SCHEMBL21430529 | 0.79 | CYP3A4 (0.52) | ALDH1A1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL12733420 | 0.79 | FKBP1A (0.66) | ALDH1A1CYP3A4CYP2C19FKBP1ANPC1 | |
| SCHEMBL20111166 | 0.78 | HDAC1 (0.61) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |