Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.55 |
| ▸ | THRB | P10828 | 14/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169743 | 1.00 | THRA (0.55) | THRATHRBGPR55 | |
| SCHEMBL2170897 | 0.92 | THRA (0.66) | THRATHRB | |
| SCHEMBL2171145 | 0.88 | THRA (0.55) | THRATHRB | |
| SCHEMBL2171146 | 0.88 | THRA (0.55) | THRATHRB | |
| SCHEMBL2169150 | 0.86 | THRA (0.50) | THRATHRB | |
| SCHEMBL2169152 | 0.86 | THRA (0.50) | THRATHRB | |
| SCHEMBL16495805 | 0.80 | THRB (0.45) | THRATHRB | |
| SCHEMBL2171901 | 0.80 | THRB (0.45) | THRATHRB | |
| SCHEMBL2169449 | 0.80 | THRB (0.66) | THRATHRB | |
| SCHEMBL2182816 | 0.80 | THRB (0.66) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2011-12-08 | — | — | US | claimed |
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2011-12-08 | — | — | US | disclosed |
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010049946-A2 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301200-A1 | THYROID RECEPTOR LIGANDS | TSHR, THRB, THRA | THRA 3/4885THRB 2/4885GPR55 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.