Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18638486 | 0.87 | NPSR1 (0.74) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL13753588 | 0.87 | NPSR1 (0.74) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL13753776 | 0.86 | NPSR1 (0.72) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL13753283 | 0.86 | NPSR1 (0.72) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL7677272 | 0.85 | NPSR1 (0.70) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL7677201 | 0.85 | NPSR1 (0.70) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL18638045 | 0.85 | TAS1R3 (0.78) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL13753648 | 0.84 | NPSR1 (0.65) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL12154445 | 0.84 | NPSR1 (1.00) | NPSR1TAS1R3TAS1R1ALDH1A1POLB | |
| SCHEMBL13753675 | 0.84 | NPSR1 (0.72) | NPSR1TAS1R3TAS1R1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452460-B1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2020-02-12 | — | — | EP | disclosed |