SCHEMBL7677201

SCHEMBL7677201

CC(CNC(=O)c1cccc(C(F)(F)F)c1)NC(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.70
ATM Q13315 1/20 0.67
POLB P06746 2/20 0.63
ALDH1A1 P00352 1/20 0.63
TAS1R3 Q7RTX0 2/20 0.62
TAS1R1 Q7RTX1 2/20 0.62
GPR139 Q6DWJ6 1/20 0.60
NPC1 O15118 1/20 0.58
CTSL P07711 1/20 0.57
TP53BP1 Q12888 1/20 0.56
KMT2A Q03164 2/20 0.54
GAA P10253 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TP53 P04637 1/20 0.53
MEN1 O00255 1/20 0.53
CCR2 P41597 2/20 0.53
P2RX1 P51575 1/20 0.51
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7677272 1.00 NPSR1 (0.70) NPSR1ATMPOLBALDH1A1TAS1R3
SCHEMBL18638486 0.86 NPSR1 (0.74) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL13753588 0.86 NPSR1 (0.74) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL7674144 0.85 POLB (0.64) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL13753283 0.85 NPSR1 (0.72) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL21697632 0.85 NPSR1 (0.72) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL13753776 0.85 NPSR1 (0.72) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL7674146 0.85 POLB (0.64) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL13257723 0.85 NPSR1 (0.64) NPSR1POLBALDH1A1TAS1R3TAS1R1
SCHEMBL18638045 0.84 TAS1R3 (0.78) NPSR1POLBALDH1A1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020052295-A1 Diacyl derivatives of propylene diamine having herbicidal activity MONSANTO TECHNOLOGY LLC 2002-05-02 US disclosed
WO-2001046152-A1 HERBICIDAL DIACYL DERIVATIVES OF PROPYLENE DIAMINE MONSANTO TECHNOLOGY LLC (US) 2001-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052295-A1 Diacyl derivatives of propylene diamine having herbicidal activity DDT, SAT1, AOC1 NPSR1 3496/4885ATM 2953/4885POLB 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.