Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | ICMT | O60725 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20218753 | 0.87 | ICMT (0.52) | TRPV1ICMTALDH1A1MAPT | |
| SCHEMBL20843606 | 0.84 | ICMT (0.47) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20218708 | 0.84 | ICMT (0.47) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20218871 | 0.82 | MAPT (0.58) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20218817 | 0.82 | ICMT (0.52) | ICMTALDH1A1MAPT | |
| SCHEMBL20218711 | 0.81 | MAPT (0.57) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL21697697 | 0.80 | MAPT (0.56) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20218620 | 0.80 | MAPT (0.56) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20218784 | 0.80 | MAPT (0.56) | ICMTALDH1A1MAPTFNTAFNTB | |
| SCHEMBL20843592 | 0.79 | MAPT (0.71) | ICMTALDH1A1MAPTFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330252-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2020-02-12 | — | — | EP | disclosed |