Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 14/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20218721 | 0.89 | ALDH1A1 (0.61) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL1819477 | 0.89 | ALDH1A1 (0.61) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL1819478 | 0.89 | ALDH1A1 (0.61) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL1819474 | 0.89 | ALDH1A1 (0.61) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL20218641 | 0.88 | ALDH1A1 (0.44) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL21697664 | 0.84 | TRPV1 (0.58) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL20843606 | 0.82 | ICMT (0.47) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL20218711 | 0.80 | MAPT (0.57) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL20218871 | 0.79 | MAPT (0.58) | ICMTMAPTALDH1A1FNTAFNTB | |
| SCHEMBL21697697 | 0.77 | MAPT (0.56) | ICMTMAPTALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3075248-B1 | USE OF ANTI-BACTERIAL AGENTS FOR THE TREATMENT OF EPITHELIAL-RELATED CONDITIONS | SIGNUM BIOSCIENCES INC (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-3330252-A2 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | Signum Biosciences, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |