SCHEMBL2169864

SCHEMBL2169864

CP1(=O)Oc2ccccc2O1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.35
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
GPR84 Q9NQS5 3/20 0.33
HPGD P15428 3/20 0.31
TSHR P16473 2/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 2/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAOA P21397 2/20 0.31
ALOX5 P09917 1/20 0.31
MAOB P27338 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598331 1.00 ABCG2 (0.35) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL16082355 0.90 HSP90AA1 (0.38) GPR84HPGDTSHRPKMLMNA
SCHEMBL20086175 0.81 TYMS (0.45) GPR84HPGDTSHR
SCHEMBL13665385 0.76 MAOA (0.34) MAOAMAOB
SCHEMBL264532 0.76 MAOA (0.34) MAOAMAOB
SCHEMBL12316480 0.76 MEN1 (0.31)
SCHEMBL4076917 0.76 MAOA (0.34) MAOAMAOB
SCHEMBL9124665 0.73 ABCG2 (0.36) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL9120606 0.71 ABCG2 (0.35) ABCG2ITGB2ICAM1ITGALGPR84
SCHEMBL12831033 0.71 ABCG2 (0.35) ABCG2ITGB2ICAM1ITGALGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11932765-B2 Meltable intumescent flame retardant compositions QED LABS, INC. (US) 2024-03-19 US claimed
US-20230331986-A1 MELTABLE INTUMESCENT FLAME RETARDANT COMPOSITIONS QED LABS INC (US) 2023-10-19 US claimed
CN-102617829-A Phosphorous-containing flame retardant epoxy waterborne self-emulsifying curing agent and application thereof CHONGQING RONGJI ENVIRONMENTAL PROT ENGINEERING CO LTD 2012-08-01 CN claimed
EP-2152793-A1 FLAME RETARDANT COMPOSITIONS BASF SE (DE) 2010-02-17 EP claimed
WO-2008151986-A1 FLAME RETARDANT COMPOSITIONS BASF SE (CH) 2008-12-18 WO claimed
US-11306414-B2 Articles with improved flame retardancy and/or melt dripping properties QED LABS INC. (US) 2022-04-19 US disclosed
US-11008458-B2 Articles with improved flame retardancy and/or melt dripping properties QED LABS INC. (US) 2021-05-18 US disclosed
US-20190048188-A1 ARTICLES WITH IMPROVED FLAME RETARDANCY AND/OR MELT DRIPPING PROPERTIES QED LABS INC. 2019-02-14 US disclosed
US-9931407-B2 Silicon based drug conjugates and methods of using same BLINKBIO, INC. (US) 2018-04-03 US disclosed
WO-2017161120-A1 ARTICLES WITH IMPROVED FLAME RETARDANCY AND/OR MELT DRIPPING PROPERTIES QED LABS INC. (US) 2017-09-21 WO disclosed
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO, INC. 2017-07-20 US disclosed
US-20160348279-A1 ARTICLES WITH IMPROVED FLAME RETARDANCY AND/OR MELT DRIPPING PROPERTIES QED LABS INC. 2016-12-01 US disclosed
US-7365113-B2 Phosphate ester flame retardants from resorcinol-ketone reaction products INDSPEC CHEMICAL CORPORATION 2008-04-29 US disclosed
US-7365113-B2 Phosphate ester flame retardants from resorcinol-ketone reaction products INDSPEC CHEMICAL CORPORATION 2008-04-29 US disclosed
US-7279515-B2 Resorcinol carbonate-based phosphate ester compounds as flame retardants INDSPEC CHEMICAL CORPORATION 2007-10-09 US disclosed
US-7279515-B2 Resorcinol carbonate-based phosphate ester compounds as flame retardants INDSPEC CHEMICAL CORPORATION 2007-10-09 US disclosed
EP-1751222-A2 LOW HEAT RELEASE AND LOW SMOKE REINFORCING FIBER/EPOXY COMPOSITES Supresta U.S. LLC. (US) 2007-02-14 EP disclosed
EP-1625171-A1 POLYPHOSPHONATE FLAME RETARDANT CURING AGENT FOR EPOXY RESIN Supresta LLC (US) 2006-02-15 EP disclosed
WO-2005118276-A2 LOW HEAT RELEASE AND LOW SMOKE REINFORCING FIBER/EPOXY COMPOSITES SUPRESTA LLC. (US) 2005-12-15 WO disclosed
WO-2004113411-A1 POLYPHOSPHONATE FLAME RETARDANT CURING AGENT FOR EPOXY RESIN SUPRESTA LLC (US) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170202970-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT ABCG2 290/4885ITGB2 525/4885ICAM1 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.