SCHEMBL216993

SCHEMBL216993

[CH]1C(Cc2ccccc2)=Cc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.48
BCL2 P10415 1/20 0.35
BCL2L1 Q07817 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ALOX5 P09917 1/20 0.35
LTA4H P09960 1/20 0.34
IDH1 O75874 2/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
IDO1 P14902 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
TRPA1 O75762 1/20 0.33
HTR2A P28223 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27948582 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27932983 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27933093 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27933181 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27933016 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27948799 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27948783 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27948589 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27948762 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB
SCHEMBL27932963 0.92 CALM1 (0.41) CALM1BCL2BCL2L1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-8748361-B2 Polyalpha-olefin compositions and processes to produce the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-06-10 US disclosed
US-20080194399-A1 Polyolefin Production with a High Performance Support for a Metallocene Catalyst System FINA TECHNOLOGY, INC. (US) 2008-08-14 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed
US-7166684-B2 Transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2007-01-23 US disclosed
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin JAPAN POLYETHYLENE CORPORATION (JP) 2006-07-27 US disclosed
US-20050233892-A1 Polyolefin production with a high performance support for a metallocene catalyst system FINA TECHNOLOGY, INC. (US) 2005-10-20 US disclosed
US-20030236365-A1 Polyolefin production with a high performance support for a metallocene catalyst system FINA TECHNOLOGY, INC. 2003-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 CALM1 3964/4885BCL2 2634/4885BCL2L1 2284/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 CALM1 4688/4885BCL2 3691/4885BCL2L1 3508/4885
US-20060167196-A1 Novel transition metal compound, catalyst for olefin polymerization and method for producing polyolefin PCLAF, ZKSCAN2, POF1B CALM1 4624/4885BCL2 3041/4885BCL2L1 1849/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 CALM1 3894/4885BCL2 4148/4885BCL2L1 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.