Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.65 |
| ▸ | DRD2 | P14416 | 18/20 | 0.65 |
| ▸ | DRD4 | P21917 | 18/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21699658 | 0.86 | HTR1A (0.68) | HTR1ADRD2DRD4KCNH2GLP1R | |
| SCHEMBL21662055 | 0.80 | DRD2 (0.57) | HTR1ADRD2DRD4KCNH2GLP1R | |
| Hydrochloric Acid SCHEMBL21642954 | 0.79 | DRD2 (0.56) | HTR1ADRD2DRD4KCNH2GLP1R | |
| SCHEMBL21662138 | 0.79 | DRD4 (1.00) | HTR1ADRD2DRD4KCNH2 | |
| SCHEMBL17001861 | 0.77 | DRD2 (0.52) | HTR1ADRD2DRD4KCNH2TLR9 | |
| SCHEMBL14861825 | 0.73 | HTR1A (0.47) | HTR1ADRD2DRD4TLR9 | |
| SCHEMBL12093559 | 0.73 | DDB1 (0.56) | HTR1ADRD2DRD4 | |
| SCHEMBL28302369 | 0.70 | DDB1 (0.50) | HTR1ADRD2DRD4 | |
| SCHEMBL29449749 | 0.70 | DDB1 (0.50) | HTR1ADRD2DRD4 | |
| SCHEMBL27939917 | 0.70 | DDB1 (0.50) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608314-A1 | 2,6-DISUBSTITUTED PYRIDINE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-02-12 | — | — | EP | disclosed |