Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988157 | 0.91 | FFAR1 (0.48) | L3MBTL1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL22562811 | 0.89 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL7229107 | 0.84 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL27746044 | 0.84 | SERPINH1 (0.48) | L3MBTL1ALDH1A1CYP2A6CYP1A2CYP2D6 | |
| SCHEMBL27746039 | 0.84 | SERPINH1 (0.48) | L3MBTL1ALDH1A1CYP2A6CYP1A2CYP2D6 | |
| SCHEMBL25336328 | 0.82 | NR1I2 (0.43) | L3MBTL1ALDH1A1SLC2A1 | |
| SCHEMBL809634 | 0.82 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1CA1CA2TDP1 | |
| SCHEMBL812999 | 0.82 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1CA1CA2TDP1 | |
| SCHEMBL2634023 | 0.81 | AOC3 (0.54) | L3MBTL1ALDH1A1CYP2A6CA12CA1 | |
| SCHEMBL9715531 | 0.81 | AOC3 (0.53) | L3MBTL1ALDH1A1CYP2A6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346863-A2 | N-SULFONAMIDO POLYCYCLIC PYRAZOLYL COMPOUNDS | Elan Pharmaceuticals Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010028213-A2 | N-SULFONAMIDO POLYCYCLIC PYRAZOLYL COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-1372703-A2 | MATRIX STABILIZED ENZYME CRYSTALS AND METHODS OF USE | IBEX TECHNOLOGIES (CA) | 2004-01-02 | — | — | EP | disclosed |
| US-20020182201-A1 | Matrix stabilized enzyme crystals and methods of use | BIOMARIN PHARMACEUTICAL INC. | 2002-12-05 | — | — | US | disclosed |
| WO-2002070646-A2 | MATRIX STABILIZED ENZYME CRYSTALS AND METHODS OF USE | IBEX TECHNOLOGIES (US) | 2002-09-12 | — | — | WO | disclosed |
| US-4742068-A | Dihydropyridine compounds having 1,4,4-trisubstitution useful as antihypertensive agents | MCNEILAB, INC. (US) | 1988-05-03 | — | — | US | disclosed |