Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370741 | 0.75 | — | — | |
| SCHEMBL8949982 | 0.75 | — | — | |
| SCHEMBL8832405 | 0.72 | — | — | |
| SCHEMBL2636200 | 0.69 | — | — | |
| SCHEMBL23026398 | 0.68 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL905769 | 0.67 | — | — | |
| SCHEMBL10580520 | 0.67 | — | — | |
| SCHEMBL964999 | 0.67 | AAK1 (0.32) | CYP1A2CYP3A4CYP2C9HIF1ATSHR | |
| SCHEMBL320287 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL21879614 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480247-B1 | NOVEL NPR-B AGONISTS | SHIRE ORPHAN THERAPIES GMBH (DE) | 2020-02-12 | — | — | EP | disclosed |