Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934866 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TDP1GPR35HPRT1CASP6 | |
| SCHEMBL18347015 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1GPR35TRPV1HPRT1 | |
| SCHEMBL30013092 | 0.81 | TDP1 (0.58) | ALDH1A1TDP1GPR35HPRT1CASP6 | |
| SCHEMBL9735773 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TDP1GPR35HPRT1CASP6 | |
| SCHEMBL187061 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TDP1GPR35HPRT1ALOX15 | |
| SCHEMBL419966 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1GPR35CASP6TSHR | |
| SCHEMBL20608200 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TDP1GPR35HPRT1CASP6 | |
| SCHEMBL9734521 | 0.79 | ALDH1A1 (0.67) | ALDH1A1TDP1GPR35HPRT1CASP6 | |
| SCHEMBL5781732 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TDP1GPR35TRPV1HPRT1 | |
| SCHEMBL7836827 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TDP1GPR35HPRT1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057588-B | Synthesis method of 8-amino-2-naphthol | 大连双硼医药化工有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114057588-A | Synthesis method of 8-amino-2-naphthol | 大连双硼医药化工有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-8618477-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2013-12-31 | — | — | US | disclosed |
| US-8492709-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120305761-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120273667-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2012-11-01 | — | — | US | disclosed |
| US-8242442-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-8217338-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2012-07-10 | — | — | US | disclosed |
| CN-102246259-A | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORP | 2011-11-16 | — | — | CN | disclosed |
| EP-2347428-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | Excellims Corporation (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20100148058-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100127166-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2010042881-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| EP-0153642-A2 | Process for the preparation of monomeric aromatic hydroxyurethanes | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |