SCHEMBL9735773

SCHEMBL9735773

O=[N+]([O-])c1cccc2cc3c([N+](=O)[O-])cccc3cc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.69
TDP1 Q9NUW8 4/20 0.67
TSHR P16473 3/20 0.55
CASP6 P55212 1/20 0.53
GPR35 Q9HC97 1/20 0.52
CYP3A4 P08684 2/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 2/20 0.50
PDE10A Q9Y233 1/20 0.50
GAA P10253 1/20 0.50
NOS1 P29475 3/20 0.49
NOS2 P35228 2/20 0.49
POLB P06746 1/20 0.48
HPRT1 P00492 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
APEX1 P27695 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30696914 0.94 ALDH1A1 (0.68) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL579426 0.94 ALDH1A1 (0.68) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL9734521 0.93 ALDH1A1 (0.67) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL5167844 0.92 ALDH1A1 (0.66) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL419966 0.86 ALDH1A1 (0.58) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL1802531 0.86 ALDH1A1 (0.58) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL11284187 0.86 ERN1 (0.56) ALDH1A1TDP1TSHRCASP6GPR35
Benzoquinone SCHEMBL28192198 0.86 ALDH1A1 (0.58) ALDH1A1TDP1TSHRCASP6GPR35
SCHEMBL8535897 0.84 ALDH1A1 (0.51) ALDH1A1TDP1TSHRCASP6CYP3A4
SCHEMBL9455556 0.84 TSHR (0.57) ALDH1A1TDP1TSHRCASP6GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107298727-B A kind of preparation and application of double salicylaldehyde imines-anthracene bimetallic titanium catalyst 青岛科技大学 2019-07-26 CN disclosed
CN-107298727-A A kind of preparation and application of double salicylaldehyde imines anthracene bimetallic titanium catalyst 青岛科技大学 2017-10-27 CN disclosed
US-5086128-A HIGH MOLECULAR WEIGHT ARYLENE SULPHIDE POLYMER MELT MIXED WITH AROMATIC NITRO COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed