Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169515 | 0.82 | CNR2 (0.51) | IRAK4SCN8ASCN10A | |
| SCHEMBL2171677 | 0.82 | CNR2 (0.51) | IRAK4SCN8ASCN10A | |
| SCHEMBL2171142 | 0.80 | CNR2 (0.55) | IRAK4SCN10AHTR2A | |
| SCHEMBL2170542 | 0.79 | LTA4H (0.55) | IRAK4SCN8ASCN10ASCN9A | |
| SCHEMBL2170712 | 0.78 | CNR2 (0.51) | IRAK4SCN8ASCN10ASCN9APARP15 | |
| Tert-Butyl Formate SCHEMBL27701436 | 0.76 | HTR2A (0.41) | IRAK4SCN8ASCN10ASCN9ACHEK1 | |
| SCHEMBL3477127 | 0.76 | TSHR (0.66) | IRAK4SCN10A | |
| SCHEMBL3443791 | 0.75 | LTA4H (0.53) | CHEK2HTR2A | |
| SCHEMBL3443522 | 0.75 | LTA4H (0.53) | CHEK2HTR2A | |
| SCHEMBL3443675 | 0.75 | LTA4H (0.53) | CHEK2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | disclosed |