Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21683252 | 1.00 | MEN1 (0.32) | MEN1KMT2ACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL21683253 | 1.00 | MEN1 (0.32) | MEN1KMT2ACYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL21683265 | 0.75 | CYP1A2 (0.34) | CYP1A2ALDH1A1CYP2C9CYP2C19PRKCA | |
| SCHEMBL21683261 | 0.75 | CYP1A2 (0.34) | CYP1A2ALDH1A1CYP2C9CYP2C19PRKCA | |
| SCHEMBL23873752 | 0.69 | ALDH1A1 (0.40) | KMT2ACYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL21701141 | 0.69 | ALDH1A1 (0.40) | KMT2ACYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16175044 | 0.62 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21701144 | 0.62 | ALDH1A1 (0.44) | KMT2ACYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1760765 | 0.58 | CYP1A2 (0.52) | MEN1KMT2ACYP1A2 | |
| SCHEMBL1760762 | 0.58 | CYP1A2 (0.52) | MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-09-30 | — | — | US | disclosed |
| WO-2020033567-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | AHR, HCCS, HMBS | MEN1 3579/4885KMT2A 2658/4885CYP1A2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.