Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701422 | 0.91 | MALT1 (0.67) | MALT1MAPTPOLBPRSS12CA1 | |
| SCHEMBL21701423 | 0.82 | POLB (0.57) | MALT1MAPTPOLBCA1CA9 | |
| SCHEMBL21701415 | 0.81 | POLB (0.67) | MAPTPOLBCA1CA9ALDH1A1 | |
| SCHEMBL21701489 | 0.79 | MAPT (0.57) | MALT1MAPTPOLBCA1CA9 | |
| SCHEMBL21701458 | 0.78 | MAPT (0.54) | MALT1MAPTPOLBALDH1A1NPSR1 | |
| SCHEMBL21701456 | 0.76 | POLB (0.57) | MALT1MAPTPOLBNPSR1F10 | |
| SCHEMBL21701410 | 0.76 | POLB (0.57) | MAPTPOLBF10KMT2AGAA | |
| SCHEMBL21701427 | 0.75 | MAPT (0.57) | MAPTPOLBF10 | |
| SCHEMBL21701605 | 0.75 | MAPT (0.57) | MAPTPOLBF10KMT2A | |
| SCHEMBL21701457 | 0.74 | ALDH1A1 (0.66) | MAPTPOLBCA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033944-A2 | NON-POLYAMINE BASED POLYAMINE TRANSPORT INHIBITORS AND THEIR USE IN THE TREATMENT OF HUMAN CANCERS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-02-13 | — | — | WO | disclosed |