Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501994 | 1.00 | L3MBTL1 (0.61) | L3MBTL1POLBRAB9AALDH1A1THRB | |
| SCHEMBL8416943 | 1.00 | L3MBTL1 (0.61) | L3MBTL1POLBRAB9AALDH1A1THRB | |
| SCHEMBL20693641 | 0.87 | KDM4E (0.47) | L3MBTL1POLBRAB9AALDH1A1THRB | |
| SCHEMBL9220591 | 0.87 | KDM4E (0.47) | L3MBTL1POLBRAB9AALDH1A1THRB | |
| SCHEMBL3982504 | 0.85 | POLB (0.53) | L3MBTL1POLBRAB9AALDH1A1ATM | |
| SCHEMBL6207733 | 0.85 | POLB (0.53) | L3MBTL1POLBRAB9AALDH1A1ATM | |
| SCHEMBL1982237 | 0.85 | POLB (0.53) | L3MBTL1POLBRAB9AALDH1A1ATM | |
| SCHEMBL12437188 | 0.84 | RAB9A (0.42) | L3MBTL1POLBRAB9AALDH1A1THRB | |
| SCHEMBL12482314 | 0.84 | POLB (0.63) | L3MBTL1POLBRAB9AMEN1KMT2A | |
| SCHEMBL28158667 | 0.84 | POLB (0.63) | L3MBTL1POLBRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030781-A1 | TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2020-02-13 | — | — | WO | disclosed |