SCHEMBL2170271

SCHEMBL2170271

CC(C)(C)C(=O)OCC(F)(F)C(F)(F)COC(=O)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.41
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ELANE P08246 3/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
BTN3A1 O00481 2/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16213966 0.91 PRKCA (0.38) PRKCAPOLBGAANPSR1HTT
SCHEMBL2693201 0.91 PRKCA (0.38) PRKCAPOLBGAANPSR1HTT
SCHEMBL17545752 0.87 PRKCA (0.36) PRKCAPOLBGAANPSR1HTT
SCHEMBL12895536 0.85 PRKCA (0.41) PRKCAPOLBGAANPSR1HTT
SCHEMBL17486700 0.85 PRKCA (0.41) PRKCAPOLBGAANPSR1HTT
SCHEMBL2692345 0.85 HTT (0.50) PRKCAPOLBGAANPSR1HTT
SCHEMBL21303906 0.85 PRKCA (0.35) PRKCAPOLBGAANPSR1
SCHEMBL26437477 0.84 PRKCA (0.33) PRKCA
SCHEMBL18031812 0.84 TSHR (0.40) PRKCAALDH1A1
SCHEMBL17545751 0.83 PRKCA (0.38) PRKCAPOLBGAANPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348010-B1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO (JP) 2014-02-26 EP disclosed
EP-2348010-B1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO (JP) 2014-02-26 EP disclosed
US-8481774-B2 Method for producing tetrafluoro compound NIPPON SODA CO., LTD. (JP) 2013-07-09 US disclosed
US-8481774-B2 Method for producing tetrafluoro compound NIPPON SODA CO., LTD. (JP) 2013-07-09 US disclosed
US-8481774-B2 Method for producing tetrafluoro compound NIPPON SODA CO., LTD. (JP) 2013-07-09 US disclosed
EP-2348010-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND Nippon Soda Co., Ltd. (JP) 2011-07-27 EP disclosed
EP-2348010-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND Nippon Soda Co., Ltd. (JP) 2011-07-27 EP disclosed
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO., LTD. (JP) 2011-07-21 US disclosed
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO., LTD. (JP) 2011-07-21 US disclosed
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND NIPPON SODA CO., LTD. (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178323-A1 METHOD FOR PRODUCING TETRAFLUORO COMPOUND F9, CA9, TAF9 PRKCA 4195/4885POLB 2054/4885GAA 3766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.