Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136782 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL2130586 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL377573 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL8411888 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL30610377 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1TDP1LMNA | |
| SCHEMBL23542536 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL8411886 | 0.80 | LTA4H (0.50) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL12425983 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL1918223 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL124384 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030663-A1 | CLEAVABLE LINKER FOR PEPTIDE SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-13 | — | — | WO | disclosed |