Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21703476 | 0.70 | MAP4K1 (0.38) | — | |
| SCHEMBL21684918 | 0.67 | MAP4K1 (0.38) | — | |
| SCHEMBL23453122 | 0.67 | NOS1 (0.33) | — | |
| SCHEMBL21703430 | 0.67 | P2RX3 (0.33) | — | |
| SCHEMBL21703094 | 0.66 | MAP4K1 (0.32) | — | |
| SCHEMBL8260735 | 0.55 | HEXA (0.52) | — | |
| SCHEMBL21703433 | 0.54 | PARP1 (0.41) | — | |
| SCHEMBL7333613 | 0.53 | APEX1 (0.40) | — | |
| SCHEMBL27280313 | 0.52 | NPSR1 (0.37) | — | |
| SCHEMBL16860594 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033784-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC. (US) | 2020-02-13 | — | — | WO | disclosed |