Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466511 | 0.73 | MAOB (0.41) | LMNAALDH1A1NPSR1MEN1MAPT | |
| SCHEMBL5795283 | 0.71 | PTGS1 (0.50) | LMNAMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL5795281 | 0.71 | PTGS1 (0.50) | LMNAMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL5795280 | 0.71 | PTGS1 (0.50) | LMNAMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL28330482 | 0.70 | MEN1 (0.37) | LMNAALDH1A1NPSR1MEN1MAPT | |
| SCHEMBL21679741 | 0.69 | — | — | |
| SCHEMBL21679743 | 0.69 | — | — | |
| SCHEMBL27593238 | 0.69 | MEN1 (0.44) | LMNAALDH1A1NPSR1MEN1MAPT | |
| SCHEMBL919332 | 0.67 | — | — | |
| SCHEMBL13566289 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-11-24 | — | — | US | disclosed |
| US-20200048233-A1 | CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF | Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd. (IL) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | FASN, ALOX5, HACL2 | LMNA 2804/4885ALDH1A1 387/4885NPSR1 1658/4885 |
| US-20200048233-A1 | CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF | FADS2, FASN, ACADM | LMNA 3698/4885ALDH1A1 188/4885NPSR1 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.