Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 8/20 | 0.41 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | TTPA | P49638 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795281 | 1.00 | PTGS1 (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL5795283 | 1.00 | PTGS1 (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL9467589 | 0.82 | PTGS1 (0.43) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9659381 | 0.76 | CYP3A4 (0.56) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9659372 | 0.76 | CYP3A4 (0.56) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL13979807 | 0.76 | CYP3A4 (0.60) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL3035038 | 0.76 | CYP3A4 (0.60) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL1286097 | 0.75 | PTGS2 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL19895323 | 0.73 | PTGS1 (0.51) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9851129 | 0.73 | MAPT (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106014-A1 | Methods for treating diabetes | ELI LILLY AND COMPANY | 2006-05-18 | — | — | US | claimed |
| WO-2006044556-A2 | DUAL INHIBITORS OF LIPOXYGENASE FOR TREATING DIABETES | GALILEO PHARMACEUTICALS, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060106014-A1 | Methods for treating diabetes | ELI LILLY AND COMPANY | 2006-05-18 | — | — | US | disclosed |
| WO-2006044556-A2 | DUAL INHIBITORS OF LIPOXYGENASE FOR TREATING DIABETES | GALILEO PHARMACEUTICALS, INC. (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106014-A1 | Methods for treating diabetes | ALOX5, ALOX15, ALOX15B | PTGS1 89/4885PTGS2 60/4885CYP1A2 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.