SCHEMBL2170423

SCHEMBL2170423

O=C(Nc1ccc(I)cc1)c1cc(I)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 5/20 0.60
KCNMA1 Q12791 1/20 0.54
TMPRSS4 Q9NRS4 4/20 0.53
ALOX15 P16050 4/20 0.50
P2RX4 Q99571 3/20 0.50
P2RX7 Q99572 3/20 0.50
LMNA P02545 2/20 0.50
PLAU P00749 4/20 0.49
F2 P00734 2/20 0.49
F10 P00742 2/20 0.49
PLAT P00750 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TOP1 P11387 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887951 1.00 P2RX1 (0.60) P2RX1KCNMA1TMPRSS4ALOX15P2RX4
SCHEMBL14223810 0.90 P2RX1 (0.77) P2RX1KCNMA1TMPRSS4P2RX4P2RX7
SCHEMBL11683814 0.90 PLAU (0.58) P2RX1KCNMA1TMPRSS4ALOX15P2RX4
SCHEMBL19024624 0.90 P2RX1 (0.57) P2RX1KCNMA1TMPRSS4ALOX15P2RX4
SCHEMBL7197436 0.90 TMPRSS4 (0.67) P2RX1KCNMA1TMPRSS4ALOX15P2RX4
SCHEMBL13997576 0.88 P2RX1 (0.51) P2RX1KCNMA1TMPRSS4ALOX15P2RX4
SCHEMBL2724088 0.88 RAB9A (0.52) P2RX1KCNMA1TMPRSS4ALOX15PLAU
SCHEMBL19040075 0.87 PLAU (0.66) P2RX1TMPRSS4ALOX15LMNAPLAU
SCHEMBL17845883 0.87 P2RX1 (0.82) P2RX1KCNMA1TMPRSS4P2RX4P2RX7
SCHEMBL23303299 0.83 TMPRSS4 (0.53) P2RX1KCNMA1TMPRSS4ALOX15P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed
EP-3628404-B1 PIPETTE TIP TRAYS BIOTIX INC (US) 2021-06-30 EP disclosed
EP-3831489-A1 PIPETTE TIPS Biotix, Inc. (US) 2021-06-09 EP disclosed
US-20210039086-A1 PIPETTE TIPS BIOTIX, INC. 2021-02-11 US disclosed
US-20210016290-A1 PIPETTE TIP RACK BIOTIX, INC. 2021-01-21 US disclosed
EP-2525910-B1 PIPETTE TIPS BIOTIX INC (US) 2020-12-09 EP disclosed
WO-2007044398-A2 ANTI-MICROBIAL PAPER PRODUCTS HAVING A SUBSTITUTED 1,2-DIHYDROQUINOLINE NOVUS INTERNATIONAL INC. (US) 2007-04-19 WO disclosed
EP-1458419-B1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2005-05-04 EP disclosed
EP-1458419-A1 ANTIMICROBIAL CONTACT LENS CASE Novartis AG (CH) 2004-09-22 EP disclosed
US-20030176530-A1 Antimicrobial contact lens case LINDLEY KAREN FRANCES (US) 2003-09-18 US disclosed
WO-2003049776-A1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2003-06-19 WO disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 US disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed