Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.52 |
| ▸ | PLAU | P00749 | 4/20 | 0.52 |
| ▸ | PLAT | P00750 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170423 | 0.88 | P2RX1 (0.60) | F10PLAUPLATF2P2RX1 | |
| SCHEMBL30887951 | 0.88 | P2RX1 (0.60) | F10PLAUPLATF2P2RX1 | |
| SCHEMBL18341044 | 0.82 | P2RX1 (0.77) | RAB9ANPC1SMN1; SMN2MAPTP2RX1 | |
| SCHEMBL11683814 | 0.82 | PLAU (0.58) | RAB9ANPC1SMN1; SMN2MAPTF10 | |
| SCHEMBL14223810 | 0.82 | P2RX1 (0.77) | P2RX1POLBKMT2AKCNMA1TMPRSS4 | |
| SCHEMBL7197436 | 0.81 | TMPRSS4 (0.67) | RAB9ANPC1P2RX1ALOX15POLB | |
| SCHEMBL13997576 | 0.79 | P2RX1 (0.51) | F10PLAUPLATF2P2RX1 | |
| SCHEMBL2724086 | 0.79 | LMNA (0.53) | RAB9ANPC1SMN1; SMN2KMT2AKCNMA1 | |
| SCHEMBL19040075 | 0.79 | PLAU (0.66) | RAB9ANPC1SMN1; SMN2F10PLAU | |
| SCHEMBL7172677 | 0.79 | TMPRSS4 (0.63) | RAB9ANPC1SMN1; SMN2MAPTP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085848-B1 | INHIBITORS OF TRANSCRIPTION FACTOR NF-KAPPA B | SMITHKLINE BEECHAM CORP (US) | 2008-01-16 | — | — | EP | claimed |
| US-20150139973-A1 | OPHTHALMOLOGICAL VEHICLE SYSTEM FOR DRUGS, OPHTHALMOLOGICAL KIT AND ALSO USE OF AN OPHTHALMOLOGICAL COMPOSITION | F. HOLZER GMBH (DE) | 2015-05-21 | — | — | US | disclosed |
| EP-2664329-A1 | Ophthalmological vehicle system | F. Holzer GmbH (DE) | 2013-11-20 | — | — | EP | disclosed |
| EP-2664330-A1 | Composition and medication containing Omega 3 fatty acids and a glucosaminoglucan | F. Holzer GmbH (DE) | 2013-11-20 | — | — | EP | disclosed |
| EP-2635266-A1 | COMPOSITION AND DRUG CONTAINING OMEGA-3 FATTY ACIDS, AND A MODULATOR | F. Holzer GmbH (DE) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059158-A1 | COMPOSITION AND DRUG CONTAINING OMEGA-3 FATTY ACIDS, AND A MODULATOR | F. HOLZER GMBH (DE) | 2012-05-10 | — | — | WO | disclosed |
| EP-1085848-B1 | INHIBITORS OF TRANSCRIPTION FACTOR NF-KAPPA B | SMITHKLINE BEECHAM CORP (US) | 2008-01-16 | — | — | EP | disclosed |