⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23938182 | 0.73 | — | — | |
| SCHEMBL21704222 | 0.73 | — | — | |
| SCHEMBL22962196 | 0.69 | CHRM2 (0.31) | — | |
| SCHEMBL23269922 | 0.69 | — | — | |
| SCHEMBL21231124 | 0.67 | — | — | |
| SCHEMBL25302147 | 0.66 | — | — | |
| SCHEMBL3702630 | 0.66 | — | — | |
| SCHEMBL23260105 | 0.65 | — | — | |
| SCHEMBL20730997 | 0.65 | — | — | |
| SCHEMBL23970669 | 0.65 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |