⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302147 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL20899713 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20899714 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL21570155 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL25405159 | 0.76 | OAT (0.41) | — | |
| SCHEMBL8356262 | 0.76 | — | — | |
| SCHEMBL23635348 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL25304661 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL25253812 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL18669715 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244613-B1 | CYCLOPROPYL AMINES CONTAINING A TETRAFLUOROMETHYL GROUP | BAYER AG (DE) | 1989-06-21 | — | — | EP | claimed |
| US-4774358-A | Cyclopropylamines containing trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | claimed |
| EP-0244613-A1 | Cyclopropyl amines containing a tetrafluoromethyl group | BAYER AG (DE) | 1987-11-11 | — | — | EP | claimed |
| EP-4692090-A1 | TRICYCLIC COMPOUND AS ATR KINASE INHIBITOR | Shanghai Fosun Pharmaceutical (Group) Co., Ltd. (CN) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024208177-A1 | TRICYCLIC COMPOUND AS ATR KINASE INHIBITOR | 上海复星医药（集团）股份有限公司 | 2024-10-10 | — | — | WO | disclosed |
| CN-113994970-B | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20220119419-A1 | BYCYCLIC JAK INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2022-04-21 | — | — | US | disclosed |
| CN-113994970-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| EP-3534709-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2019-09-11 | — | — | EP | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| CN-110191639-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2019-08-30 | — | — | CN | disclosed |
| US-8551981-B2 | Furo[3,2-d]pyrimidine compounds | ABBVIE INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120122846-A1 | FURO[3,2-d]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |
| EP-0244613-B1 | CYCLOPROPYL AMINES CONTAINING A TETRAFLUOROMETHYL GROUP | BAYER AG (DE) | 1989-06-21 | — | — | EP | disclosed |
| US-4774358-A | Cyclopropylamines containing trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| EP-0244613-A1 | Cyclopropyl amines containing a tetrafluoromethyl group | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |