SCHEMBL25302147

SCHEMBL25302147

N[C@@H]1C[C@H]1C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702630 1.00
Hydrochloric Acid SCHEMBL20899713 0.97
Hydrochloric Acid SCHEMBL20899714 0.97
Hydrochloric Acid SCHEMBL21570155 0.97
Hydrochloric Acid SCHEMBL25405159 0.76 OAT (0.41)
SCHEMBL8356262 0.76
SCHEMBL23635348 0.74
Hydrochloric Acid SCHEMBL25304661 0.71
Hydrochloric Acid SCHEMBL25253812 0.71
Hydrochloric Acid SCHEMBL18669715 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452944-A1 CYCLOPROPYL COMPOUNDS Icagen, LLC (US) 2024-10-30 EP disclosed
US-20240336571-A1 NOVEL CYCLOPROPYL COMPOUNDS ANGELINI PHARMA S.P.A. (IT) 2024-10-10 US disclosed
WO-2023121992-A1 CYCLOPROPYL COMPOUNDS ICAGEN, LLC (US) 2023-06-29 WO disclosed