SCHEMBL21704260

SCHEMBL21704260

CN[C@H]1CCN(c2ccc3c(c2)CCCC3)C1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 19/20 0.53
AXL P30530 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27389150 0.74 HRH4 (0.54) HRH4
SCHEMBL2636071 0.74 HRH4 (0.54) HRH4
SCHEMBL30230101 0.74 HRH4 (0.54) HRH4
SCHEMBL22184436 0.74 HRH4 (0.54) HRH4
SCHEMBL16695411 0.74 MAPT (0.47)
SCHEMBL22297112 0.74 HRH4 (0.52) HRH4
SCHEMBL18551436 0.74 HRH4 (0.52) HRH4
SCHEMBL26375959 0.74 HRH4 (0.52) HRH4
SCHEMBL22400180 0.73 HRH4 (0.50) HRH4AXL
SCHEMBL19904646 0.73 HTR6 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020033707-A1 CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS FORMA THERAPEUTICS, INC. (US) 2020-02-13 WO disclosed