Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21704834 | 0.96 | RAF1 (0.30) | RAF1BRAFALKMGAT2 | |
| SCHEMBL21704835 | 0.95 | RAF1 (0.31) | MCHR1RAF1BRAFALKTP53 | |
| SCHEMBL21704931 | 0.95 | MCHR1 (0.32) | MCHR1ALKMGAT2TP53 | |
| SCHEMBL29295058 | 0.95 | RAF1 (0.31) | MCHR1RAF1BRAFALK | |
| SCHEMBL29295072 | 0.91 | RAF1 (0.30) | RAF1BRAFALK | |
| SCHEMBL29295068 | 0.91 | PLG (0.31) | MCHR1ALKTP53 | |
| SCHEMBL21704836 | 0.91 | — | — | |
| SCHEMBL21681706 | 0.90 | RAF1 (0.31) | RAF1BRAFALK | |
| SCHEMBL12581582 | 0.89 | ALK (0.34) | MCHR1RAF1BRAFALKMGAT2 | |
| SCHEMBL1963611 | 0.89 | ALK (0.34) | MCHR1RAF1BRAFALKMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621958-B1 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-07-10 | — | — | EP | disclosed |
| US-20200048216-A1 | Photochromic Indeno Fused Phenanthrenopyran Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048216-A1 | Photochromic Indeno Fused Phenanthrenopyran Compounds | ALDH1A2, RB1, INCENP | MCHR1 288/4885RAF1 4654/4885BRAF 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.