Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ATR | Q13535 | 3/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706589 | 0.90 | KDM4E (0.70) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| Omilancor SCHEMBL17706588 | 0.89 | LANCL2 (1.00) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| Omilancor SCHEMBL29349469 | 0.89 | LANCL2 (1.00) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL21043129 | 0.86 | LANCL2 (0.93) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL25310542 | 0.84 | LANCL2 (0.76) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL18805072 | 0.83 | LANCL2 (0.88) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL17705594 | 0.83 | LANCL2 (0.88) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL25877324 | 0.82 | LANCL2 (0.59) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL29466338 | 0.82 | LANCL2 (0.86) | LANCL2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL25877375 | 0.82 | LANCL2 (0.86) | LANCL2KDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10682349-B2 | Lanthionine synthetase C-like 2-based therapeutics | LANDOS BIOPHARMA, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20200046694-A1 | LANTHIONINE SYNTHETASE C-LIKE 2-BASED THERAPEUTICS | LANDOS BIOPHARMA, INC. (US) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10682349-B2 | Lanthionine synthetase C-like 2-based therapeutics | LANCL2, CBS, LCP2 | LANCL2 1/4885KDM4E 3829/4885NPC1 1574/4885 |
| US-20200046694-A1 | LANTHIONINE SYNTHETASE C-LIKE 2-BASED THERAPEUTICS | LANCL2, CBS, LCP2 | LANCL2 1/4885KDM4E 3829/4885NPC1 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.