Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23970311 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL26569766 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL16330602 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL10271866 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL14707099 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL23435745 | 0.77 | NCF1 (0.41) | DPP4 | |
| SCHEMBL12462467 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL25353980 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL14543511 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL24571398 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033514-A1 | BENZIMIDAZOLE INHIBITORS OF PAD ENZYMES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-02-13 | — | — | WO | disclosed |