SCHEMBL21705613

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21705598	0.91	TSHR (0.61)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL26809424	0.86	PHLPP2 (0.45)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL26807523	0.84	PHLPP2 (0.51)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL21705606	0.84	TSHR (0.72)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL21705611	0.82	TSHR (0.52)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL26809605	0.81	PHLPP2 (0.50)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL12661910	0.81	ALDH1A1 (0.52)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL34468111	0.80	PHLPP2 (0.71)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL26807545	0.80	PHLPP2 (0.57)	CYP2D6TSHRMAOAHRH3HTR3A
	SCHEMBL13291855	0.78	TDP1 (0.56)	CYP2D6TSHRLMNAGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.