Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.75 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.63 |
| ▸ | ITGAM | P11215 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21706057 | 0.86 | ITGB3 (0.66) | ITGB3ITGA2BITGB2ITGAM | |
| Roxifiban SCHEMBL24336949 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Roxifiban SCHEMBL344302 | 0.86 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Roxifiban SCHEMBL919675 | 0.84 | ITGB3 (0.95) | ITGB3ITGA2B | |
| SCHEMBL21705409 | 0.82 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL25802365 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL24336948 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2B | |
| SCHEMBL26480344 | 0.82 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL7090791 | 0.82 | ITGB3 (0.89) | ITGB3ITGA2BITGB2ITGAM | |
| SCHEMBL21705414 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033724-A1 | INTEGRIN ANTAGONISTS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-02-13 | — | — | WO | disclosed |