Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444353 | 1.00 | MAP3K5 (1.00) | MAP3K5HPGD | |
| SCHEMBL20755687 | 0.86 | MAP3K5 (0.76) | MAP3K5 | |
| SCHEMBL945832 | 0.82 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL29473528 | 0.82 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL946755 | 0.81 | MAP3K5 (0.78) | MAP3K5 | |
| SCHEMBL943924 | 0.81 | MAP3K5 (0.78) | MAP3K5 | |
| SCHEMBL17305877 | 0.81 | MAP3K5 (0.80) | MAP3K5 | |
| SCHEMBL945181 | 0.81 | MAP3K5 (0.75) | MAP3K5 | |
| SCHEMBL945441 | 0.81 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL12946065 | 0.81 | MAP3K5 (0.77) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111107848-B | Pharmaceutical composition containing amide derivatives, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-109983007-B | Amide derivative inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-11-05 | — | — | CN | disclosed |
| US-11136324-B2 | Substituted imidazoles as apoptosis signal regulating kinase 1 inhibitors | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-10-05 | — | — | US | disclosed |
| US-20210032249-A1 | AMIDE DERIVATIVE INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-02-04 | — | — | US | disclosed |
| CN-111107848-A | Pharmaceutical composition containing amide derivatives, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-05-05 | — | — | CN | disclosed |
| WO-2020030107-A1 | PHARMACEUTICAL COMPOSITION CONTAINING AMIDE DERIVATIVES, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210032249-A1 | AMIDE DERIVATIVE INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF | AADAC, CHUK, TFPI | MAP3K5 26/4885HPGD 1194/4885 |
| US-11136324-B2 | Substituted imidazoles as apoptosis signal regulating kinase 1 inhibitors | AIFM1, IRAK1, CASP1 | MAP3K5 14/4885HPGD 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.