SCHEMBL21706280

SCHEMBL21706280

CC1=C[C@@]2(CC[C@H]3CC=C(C)C(=O)[C@@H]3O2)OC1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.34
POLE3 Q9NRF9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21706276 0.68 PTPN11 (0.41) PTPN11
SCHEMBL21673037 0.59 PTPN11 (0.57) PTPN11POLE3
SCHEMBL9717624 0.52
SCHEMBL20552104 0.52 ALDH1A1 (0.31)
SCHEMBL10347729 0.52 TAS2R46 (0.35)
SCHEMBL18982983 0.51
SCHEMBL11859804 0.50 MEN1 (0.32) PTPN11POLE3
SCHEMBL32678445 0.50 PTPN11 (0.36) PTPN11POLE3
SCHEMBL32678441 0.50 PTPN11 (0.36) PTPN11POLE3
SCHEMBL32678444 0.50 PTPN11 (0.36) PTPN11POLE3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020033286-A1 NOVEL SESQUITERPENOID ANALOGS PURDUE RESEARCH FOUNDATION (US) 2020-02-13 WO disclosed