SCHEMBL2170644

SCHEMBL2170644

C=CC(C)[SiH](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.34
LMNA P02545 1/20 0.34
LTA4H P09960 2/20 0.32
TSHR P16473 2/20 0.32
MAOA P21397 1/20 0.32
PTGS1 P23219 1/20 0.32
ALDH1A1 P00352 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704478 0.76 CA4 (0.42) CA4LMNALTA4HTSHRMAOA
SCHEMBL2168155 0.76 CYP2C19 (0.36) CA4LMNAMAOAPTGS1ALDH1A1
SCHEMBL9496220 0.73 LMNA (0.32) CA4LMNALTA4HTSHRMAOA
SCHEMBL2229317 0.72 CA4 (0.39) CA4LMNALTA4HTSHRMAOA
SCHEMBL704613 0.72 CA4 (0.39) CA4LMNALTA4HTSHRPTGS1
SCHEMBL19725367 0.71 KDM4E (0.38) CA4LMNALTA4HTSHRMAOA
SCHEMBL19927436 0.71 CA4 (0.42) CA4LMNALTA4HTSHRMAOA
SCHEMBL28453789 0.71 POLB (0.40) LMNALTA4HMAOAPTGS1ALDH1A1
SCHEMBL19927430 0.70 CA4 (0.40) CA4LMNALTA4HTSHRMAOA
SCHEMBL6143132 0.69 LMNA (0.39) CA4LMNALTA4HTSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed