SCHEMBL21706474

SCHEMBL21706474

Cc1ccc(C2(c3ccc(C)cc3)c3cc(-c4ccc(C=O)s4)ccc3-c3sc4c5c(sc4c32)-c2ccc(-c3ccc(C=O)s3)cc2C5(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRF1 P14222 8/20 0.42
PGR P06401 1/20 0.42
MAPT P10636 1/20 0.36
APP P05067 1/20 0.35
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20043836 0.93 PGR (0.43) PRF1PGRMAPTAPPCYP2E1
SCHEMBL23278536 0.89 PRF1 (0.43) PRF1PGRMAPTAPPCYP2E1
SCHEMBL20365628 0.85 PGR (0.42) PRF1PGRMAPTAPPCYP2E1
SCHEMBL20044280 0.82 PGR (0.35) PRF1PGRMAPTAPPCYP2C9
SCHEMBL20247154 0.81 PGR (0.32) PRF1PGR
SCHEMBL23082566 0.80 CYP2A6 (0.39) MAPTCYP2A6
SCHEMBL20043746 0.79 PRF1 (0.36) PRF1PGRMAPTAPP
SCHEMBL20042465 0.78 PRF1 (0.35) PRF1PGRAPP
SCHEMBL20044395 0.78 PRF1 (0.35) PRF1PGRAPP
SCHEMBL20044318 0.78 PRF1 (0.37) PRF1PGRMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-10991893-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-04-27 US disclosed
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC PRF1 3167/4885PGR 1755/4885MAPT 32/4885
US-10991893-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC PRF1 3167/4885PGR 1755/4885MAPT 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.