SCHEMBL20043836

SCHEMBL20043836

Cc1ccc(C2(c3ccc(C)cc3)c3cc(-c4ccc(C=O)s4)ccc3-c3sc4c(c32)C(c2ccc(C)cc2)(c2ccc(C)cc2)c2cc(-c3ccc(C=O)s3)ccc2-4)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.43
PRF1 P14222 6/20 0.41
MAPT P10636 2/20 0.37
APP P05067 1/20 0.36
CYP2A6 P11509 2/20 0.34
CYP2E1 P05181 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 2/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
DPP4 P27487 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21706474 0.93 PRF1 (0.42) PGRPRF1MAPTAPPCYP2A6
SCHEMBL20044280 0.88 PGR (0.35) PGRPRF1MAPTAPPCYP2C9
SCHEMBL20365628 0.87 PGR (0.42) PGRPRF1MAPTAPPCYP2A6
SCHEMBL23278536 0.82 PRF1 (0.43) PGRPRF1MAPTAPPCYP2A6
SCHEMBL20247154 0.79 PGR (0.32) PGRPRF1
SCHEMBL20246959 0.77 PGR (0.35) PGRPRF1MAPTKDM4EALDH1A1
SCHEMBL21949336 0.77 PGR (0.35) PGRPRF1MAPTKDM4EALDH1A1
SCHEMBL9538845 0.76 APP (0.54) PGRPRF1MAPTAPPCYP2A6
SCHEMBL21709685 0.76 KMT2A (0.35) PRF1MAPTAPPHPGDALDH1A1
SCHEMBL20043832 0.76 RAB9A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-10759775-B2 Organic semiconducting compounds MERCK PATENT GMBH (DE) 2020-09-01 US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
WO-2018065352-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed
WO-2018065356-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10759775-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC PGR 1261/4885PRF1 3118/4885MAPT 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.